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Research

Phytochemicals

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By: Sean Moloughney

Editor, Nutraceuticals World

Indication: Ovarian cancer

Source: J Nutr, 2003 Jun;133(6):1937-42.

Research: Intakes of specific nutrients and food groups have been shown previously to be related to ovarian cancer risk, but no studies, according to the study’s researchers, have emphasized the effect of phytochemical intakes on this cancer. A case-control study of diet and ovarian cancer in Western New York involving 124 primary, histologically confirmed ovarian cancer cases and 696 population-based controls was conducted. Diet was assessed with a detailed food-frequency questionnaire and nutrient and phytochemical intakes were calculated from published food composition data.

Results: Compared with women in the lowest quintile of intake, reduced risks were observed for women in the highest quintile of intake of dietary fiber, total carotenoids, stigmasterol, total lignans, vegetables and poultry. These results, according to researchers, support a protective effect on ovarian cancer of phytoestrogen intakes. Additionally, re­searchers said the results support the hypothesis that a plant-based diet may be important in reducing risks of hormone-related neoplasms.

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